KUTIS Tretiva Rx Tretinoin 0.5%; turn back the clock and transform your skin with this dermatologist-strength retinol serum. Tretiva Rx 0.5% works deep below the surface to smooth fine lines, clear breakouts, fade dark spots, and boost collagen—all while you sleep. Formulated for maximum results with minimal irritation, it’s your nightly dose of skin renewal. Wake up to clearer, firmer, more radiant skin.